Bactrim - a combined drug, containing two active ingredients: sulfanamide drug sulfamethoxazole and derivative of diaminopyrimidine - trimethoprimum. Colibacillus life activity oppresses that leads to reduction of synthesis of thymine, riboflavinum, niacin, etc. group B vitamins in intestines. Duration of therapeutic effect makes 7 years.
An antifungal agent from the group of imidazole derivatives for external and local applications reduces the synthesis of ergosterol, which is a part of the cell membrane of the microbial wall and leads to a change in its structure and properties. In fungicidal concentrations, it interacts with mitochondrial and peroxidase enzymes, leading to an increase in the concentration of hydrogen peroxide to toxic levels, which also contributes to the destruction of fungal cells. The pills are active against pathogenic dermatophytes, pathogens of multi-colored lichen, erythrasma, gram-positive and gram-negative bacteria.
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It is also important to note, however, that the use of cannabis for treating epilepsy could result in additional, unwanted side effects such as decreased appetite, ability to perform daily functions such as driving, or memory issues, which can ultimately diminish their efficacy against treatment-resistant epilepsy.
"As the potential effects of cannabinoids on the brain continue to evolve we will be continually refining and improving the efficacy safety of treatment," said Dr. Michael J. Sessa, Vice President Medical Affairs and Chief Officer for Sativex. "The Phase III clinical trial is a critical step in this process. By demonstrating that Sativex is safe and efficacious, it will assist us as we continue the evaluation of Sativex for new and different indications in the future, to ensure its continued development and safety of its drug constituents and for medical canadian pharmacy generic viagra use globally."
This study received partial funding from the Canadian Institutes of Health Research (CIHR) and the Canadian Center for Advancement of Healthcare Innovation (CCAHI). Part the funding came from Canadian Institutes of Health Research (CIHR) and part was from the Fonds de la recherche du Québec – Sainte-Famille Health Initiative (FRQ) and the Canadian Institutes of Health Research (CIHR).
About Sativex®
Sativex® (nabilone) is a patented therapeutic cannabis product for the symptomatic treatment of spasticity-related complex (SPCR – chronic, severe and painful muscle spasms, including epilepsy) in patients over the age of 18. Sativex is manufactured by an independent pharmaceutical company specializing in the proprietary synthesis of cannabis compounds.
About GW Pharmaceuticals plc
Founded in 1998, GW is one of the world's largest developers and producers of genetically modified organisms (GMOs) and cannabinoid medicines. GW has a strong track record of science and engineering innovation in cannabis is the global leader in cannabinoid research and biopharmaceuticals. October 2014, GW applied to the US Food and Drug Administration for a new to treat epilepsy, disease affe
